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9 Natural Plant Extracts for Antidepressant

Views: 14     Author: Ellie     Publish Time: 2019-09-17      Origin: Site

Depression is a huge problem in modern society. Whether it is celebrities or ordinary people, more and more people are suffering from depression. Depression not only plagues patients and the people around them, but also because they are difficult to get safe and Effective treatment is getting worse. Compared with antidepressants, most consumers prefer natural plant extracts or herbs to relieve, with high safety and side effects. As research continues to deepen, natural plant extracts will hold up half the sky in antidepressant future.

 plant extract

In the treatment of depression, in addition to psychological communication therapy, antidepressants are more common at present, but most drugs have side effects and will produce certain drug resistance, which will have adverse effects on the health of the human body. Compared with antidepressants, most consumers prefer natural plant extracts or herbs to relieve, with high safety and side effects. As research continues to deepen, natural plant extracts will hold up half the sky in antidepressant future.

 

Anacycli pyrethri radix extract

Anacycli pyrethri radix extract, also known as akarkara, is a unique Ayurvedic herb in India. It is characterized by aromatic roots and a strong taste. It promotes the flow of saliva and the burning taste, and is often used in areas such as Southeast Asia to treat toothache, sore throat and colds. It has been used to help the nervous system since ancient times and has also been used to treat premature ejaculation and impotence.

 

In a recent study, researchers began to determine whether the extract of anacycli pyrethri radix (APRE) in southern Europe would have an effect on depression in mice. They studied mice with depression and conducted a series of tests to observe changes in their behavior and analyzed their blood.

 

The researchers determined that the extract of P. chinensis in southern Europe did have antidepressant effects, which they believed were due to the cortisol reduction of the extract and the ability to promote 5-HT neurological function.

 

Saffron extract

Saffron extract is a medicinal material. The main ingredients are saffron acid and crocin. It has the effects of calming, phlegm and phlegm, and can be used for the treatment of stomach diseases, menstruation, measles, fever, jaundice, hepatosplenomegaly and the like.

 

Saffron extract has proven to be effective as a natural antidepressant in several clinical trials. The crocin and crocetin found in the petals and stigma of plants are believed to be responsible for this effect. Various studies have shown that it is as effective as prescription drugs such as Prozac.

 

5-HTP

5-hydroxytryptophan (5-HTP) is mainly extracted from African Ghana seed extract (Griffonia), and is also an essential amino acid produced by the brain, which can control the content of human serotonin (also known as serotonin, 5-HT). . 5-HT is a neurotransmitter that produces pleasant emotions in the brain. It can affect almost every aspect of brain activity, from regulating mood, energy, memory and even shaping life. 5-HTP is the precursor of 5-HT, which produces 5-HT under the action of decarboxylase, which can increase the production of serotonin in brain cells and increase the content of 5-HT. In recent years, the increase in 5-HTP demand is mainly caused by changes in people's lifestyles, incorrect eating habits and hormone secretion disorders, and people's mental stress is gradually increasing, so the demand for natural ingredients against depression is also increasing. Importantly, 5-HTP is superior to tryptophan as a natural plant extract that alleviates depression, as most tryptophan is chemically synthesized. According to a recent data from Transparency Market Research, the 5-HTP market has reached $31.7 million in 2012, and is expected to reach $51.4 million in 2019, with a compound annual growth rate of 7.1%. As people's brain health and sleep demand grows, the future of 5-HTP will be more widely used worldwide.

 St.John's Wort

Hypericum perforatum extract

Hypericum perforatum L belongs to the genus Garcinia, Hypericum, and is also known as St. John's Wort in the West. A number of studies have shown that Hypericum perforatum achieves antidepressant effects by inhibiting the recovery of 5-HT and monoamine oxidase, acting on dopamine and norepinephrine. Hypericin contained in Hypericum perforatum is the main component of depression relief, with the highest content of petals. In Germany, all the treatments for depression, the use of St. John's wort is 40%, and its effect is similar to Prozac (a more common antidepressant). A 2016 study involving 14 960 adults showed that 500 to 1800 mg of St. John's wort extract daily can significantly relieve depression, which is no less effective than antidepressant prescription drugs. The study found that Hypericum perforatum extract improves mood by reducing the body's resorption of serotonin, dopamine and norepinephrine.

 

Stevia extract

Lampranthus spectabilis is a perennial herb of the genus Apricot. It has slender stems and rich colors. A study conducted jointly by the University of Utrecht in the Netherlands and the University of Cape Town in South Africa showed that the extract of the stevia has a certain effect on the dual activities of PDE4 and 5-HT reuptake inhibition in the brain, thus contributing to human management pressure. A deep understanding of emotions. The researchers recruited 16 healthy college students and randomly divided them into two groups. One group was given 25 mg of stevia extract and the other group was given a placebo. The results showed that in the 2-hour mood management, the depression of the drug group subjects was relieved. In addition, African indigenous people have used the plant for many years to regulate mood and alleviate depression.

 

Broccoli extract

A study published by the Center for Social Mental Health Education of Chiba University in Japan has shown that broccoli-derived sulforaphane (SFN) has the effect of preventing depression and inhibiting the recurrence of depression. The research team found that normal healthy mice were able to drink 70%-80% sucrose water, while stressed depression mice could only drink about 50% sugar water. However, if the SFN is fed before the mice are in a state of depression, the depression in the rats is similar to that of the normal mice, thus avoiding the appearance of depressive symptoms. In addition, the researchers injected SFN precursors into young rats to confirm a significant increase in their ability to withstand stress.

 

Griffin mushroom extract

Earlier studies have shown that P. sinensis (H. edulis) has potential applications in promoting brain cognitive health. A 2015 study found that prion mushroom can relieve depression by lowering certain levels of inflammatory factors. This experiment found that the imbalance of proinflammatory cytokines, tumor necrosis factor-α and interleukin-10 in serum can lead to depression, while the extract of prion mushroom has clear antidepressant effect in serum and behavior. It is comparable to Paroxetine and will be studied in depth in the future.

 

Rhodiola extract

Rhodiola is a perennial herb or subshrub plant of Rhodiola L. It is often fleshy. Its roots and rhizomes can be as medicine, and sometimes whole grass can be used. Modern research has shown that Rhodiola has antioxidant, increased exercise tolerance, improved immunity, anti-depression and whitening effects. Animal experiments have shown that Rhodiola rosea extract can increase the transmission rate of serotonin precursors tryptophan and 5-HTP in the brain. Unstable serotonin often causes depression and depression. An article published in the 2015 Plant Medicine pointed out that Rhodiola rosea extract can alleviate the condition of patients with mild to moderate depression (MDD). Although the antidepressant effect is no less than traditional antidepressant drugs, the side effects are significantly less. In addition, Rhodiola can improve sleep quality by protecting the nervous system from oxidative stress damage.

 Curcumin

Curcumin

A 2013 study by the Baylor Institute in the United States showed for the first time that curcumin is more effective in alleviating mild to moderate depression, and the antidepressant effect is similar to that of fluoxetine, and there is no adverse reaction. As research progresses, a 2014 study in Australia found that curcumin may relieve symptoms of severe depression, especially atypical depression. The study suggests that the mechanism of action of curcumin is related to its potent anti-inflammatory properties and may be related to the biological mechanisms associated with depression, including monoamine activity, immune inflammation, oxidative and nitrosative stress pathways, and hypothalamic-pituitary-adrenal gland. Axis (HPA), in the future, more large-scale, longer-term and different dose studies are needed to verify the effects of curcumin on depression.

 


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