High Quality 98% Ursolic Acid Manufacturer Loquat Leaf Extract Ursolic Acid
Ursolic acid is a chemical product, formerly known as Ursolic Acid. The high content of ursolic acid is glossy prismatic (anhydrous ethanol) or fine hair-like needle crystal (dilute ethanol), the low content is brownish yellow or yellow-green powder, with a special smell, is one of the natural plants A five-ring triterpenoid compound.
Melting point 283 ~ 288 ℃. Specific optical rotation [α] D25 + 67.5 ° (C = 1,1mol / L potassium hydroxide in alcohol solution). At 15 ℃, ethanol (99%) 1 ml can dissolve 10 mg, boiling 1 ml can dissolve 45 mg. Insoluble in water, still in methanol, ethanol, acetone, pyridine.
Ursolic acid function:
1.Antioxidant and sedative.Healing chronic respiratory conditions such as bronchitis.
2.Beautifying skin and healing inflammatory skin conditions such as psoriasis and eczema.
3.Reducing blood sugar and anti diabetic.
4.Antibacterial effect and anti ulcer.
Ursolic acid application:
1 Liver protection, anti-hepatitis effect
Ursolic acid clinically has significant and rapid effects of reducing alanine aminotransferase, serum aminotransferase, eliminating jaundice, increasing appetite, anti-fibrosis and restoring liver function, and has the characteristics of quick effect, short treatment course and stable effect.
2 Antitumor effect
Ursolic acid is also resistant to a variety of carcinogens and carcinogens. Studies have found that ursolic acid can significantly inhibit the proliferation of HL-60 cells and induce apoptosis: it can significantly increase the phagocytic function of mouse macrophages It can inhibit the proliferation of human tongue squamous cell carcinoma cell line TSCCa, and the inhibitory amount of half of the growth of TSCCa cells is about 12.5μmolL-1, which shows a fixed dose-effect relationship within 24h: in situ hybridization shows that ursolic acid has a good effect on The inhibitory effect of cells is related to the suppression of in situ expression of nuclear transcription factors. . In vivo tests prove that ursolic acid can significantly enhance the body's immune function. It shows that ursolic acid has a wide range of anti-tumor effects, and ursolic acid is very likely to become a new anti-cancer drug with low toxicity and effectiveness.