Introduction of Vitamin A Acid Retinoic Acid CAS 4759-48-2 Isotretinoin
Isotretinoin (13-cis-Retinoic acid )is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. Clinically, 13-cis-Retinoic acid is primarily used in the treatment of severe recalcitrant nodular acne. Its effects include reducing the production of sebum, shrinking the size of the sebaceous glands, stabilizing keratinization, preventing comedones from forming, and reducing inflammation of inflammatory acne. Though the exact mechanism of action of 13-cis-Retinoic acid is not fully understood, studies have suggested that the compound alters DNA transcription and induces apoptosis in select types of cells throughout the body.
Function of Vitamin A Acid Retinoic Acid CAS 4759-48-2 Isotretinoin
Both tretionirum and Vitamin A can stimulate skin growth and keep epidermic normal. Howerver, to spread on part of skin has no actual effect. Taking orally vitamin A is benefit to treat skin disorders. Applying vitamin A acid to skin partly could produce intensive pharmacological action. External use can slow down skin aging process for solarization, remove tiny wrinkles, and reduce skin roughness, so skin will become ruddy.
Side-effect and Notice:
Don`t spread it in thin skin. Proper lower concentration (no more than 0.025%)can avoid such reaction as scalp off, Scorching fever and erythema, which is caused by drastic dilation of blood vessel. Please insist on using the product and you will get preferable curative effect when you find such normal reaction as erythema, scorch fever and hypodynia. Discontinue it and apply some oleiferous skin-care products to the skin site, if the reaction is severe. Cold cream concentration less than 0.025, show some effect upon treating acne and skin roughness kept cool and closed.
Application Of of Vitamin A Acid Retinoic Acid CAS 4759-48-2 Isotretinoin
1. Retinoic Acid/Tretinoin is widely applied in pharmaceutical field, mainly used for the cure of dermatonosus like acne, ichthyosis and psoriasis abnormal, etc..
Retinoic Acid/Tretinoin can be made into tretinoin or retinoic acid cream to cure acne or other unhealthy skin.
2. Retinoic Acid/Tretinoin is used for skin keratinocytes-resistant drugs and cell-
induced differentation drug.